Publications


Scientific papers

Amadasi A, Mozzarelli A, Meda C, Maggi A, Cozzini P. (2008) Identification of xenoestrogens in food additives by an integrated in silico and in vitro approach. Chemical Research in Toxicology 2008 Dec 8. [Epub ahead of print]

Antal MC, Krust A, Chambon P, Mark M. (2008) Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. Proc Natl Acad Sci U S A 105:2433-8.

Ashworth J, Gilliver S and Ashcroft GS. (2007) The hormonal regulation of cutaneous wound healing. Clinics in Dermatology, 12, 7.

Barreto G, Veiga S, Azcoitia I, Garcia-Segura LM, Garcia-Ovejero D. (2007) Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites oestradiol and dihydrotestosterone. European Journal of Neuroscience 25,3039–3046.

Billon-Galès A, Fontaine C, Filipe C, Douin-Echinard V, Fouque M-J, Flouriot G, Gourdy P, Lenfant F, Laurell H, Krust A, Chambon P, Arnal J-F. The transactivating function 1 of estrogen receptor α is dispensable for the vasculoprotective actions of 17beta-estradiol. Proc Natl Acad Sci U S A. In press.

Brufani M, Ceccacci F, Filocamo L, Garofalo B, Joudioux R, La Bella A, Leonelli F, Migneco LM, Marini Bettolo R, Farina PM, Ashcroft GS, Routley C, Hardman M, Meda C, Rando G, Maggi A. (2009) Novel locally active estrogens accelerate cutaneous wound healing. A Preliminary Study. Molecular Pharmacology 2009 Jan 14. [Epub ahead of print]

Cardona-Gomez GP, Arango-Davila C, Gallego-Gomez JC, Barrera-Ocampo A, Pimienta H, Garcia-Segura LM. (2006) Estrogen dissociates Tau and alpha-amino-3-hydroxy-5- methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus. Neuroreport 17,1337-1341.

Cignarella A, Bolego C, Pelosi V, Meda C, Krust A, Pinna C, Gaion RM, Vegeto E, Maggi A. (2009) Distinct roles of estrogen receptor-alpha and beta in the modulation of vascular inducible nitric-oxide synthase in diabetes. Journal of Pharmacology and Expermental Therapeutics. 328:174-182. [Epub 2008 Oct 2]DonCarlos LL, Azcoitia I, Garcia-Segura LM. (2007) In search of neuroprotective therapies based on the mechanisms of estrogens. Expert Review of Endocrinology and Metabolism 2,387- 397.

Garcia-Segura LM. (2008) Aromatase in the brain: not just for reproduction anymore. Journal of Neuroendocrinology 20:705-712.

Garcia-Segura LM, Lorenz B, DonCarlos LL. (2008) The role of glia in the hypothalamus: implications for gonadal steroid feedback and reproductive neuroendocrine output. Reproduction 135:419-429.

Garcia-Segura LM, Diz-Chaves Y, Perez-Martin M, Darnaudéry M. (2007) Estradiol, insulin-like growth factor-I and brain aging. Psychoneuroendocrinology 32, Suppl 1:557-561.

Garcia-Segura LM, Melcangi RC. (2006) Steroids and glial cell function. Glia 54,485-498.

Garcia-Segura LM, Sanz A, Mendez P. (2006) Cross-talk between IGF-I and estradiol in the brain: Focus on neuroprotection. Neuroendocrinology 84,275-279.

Gilliver S and Ashcroft GS. (2007) Impaired wound healing in elderly women. Climacteric, 10, 8

Guerra-Araiza C, Amorim MA, Pinto-Almazán R, González-Arenas A, Campos MG, Garcia-Segura LM. (2008) Regulation of the phosphoinositide-3 kinase and mitogen-activated protein kinase signaling pathways by progesterone and its reduced metabolites in the rat brain. Journal of Neuroscience Research, in press

Hardman MJ, Emmerson E, Campbell L, Ashcroft GS. (2008) Selective estrogen receptor modulators accelerate cutaneous wound healing in ovariectomized female mice. Endocrinology 149, 551-557.

Melcangi RC, Garcia-Segura LM, Mensah-Nyagan AG. (2008) Neuroactive steroids: State of the art and new perspectives. Cellular and Molecular Life Sciences 65:777-797.

Mendez P, Wandosell F, Garcia-Segura LM. (2006) Cross-talk between estrogen receptors and insulin-like growth factor-I receptor in the brain: Cellular and molecular mechanisms. Frontiers in Neuroendocrinology 27,391-403.

Morissette M, Le Saux M, D'Astous M, Jourdain S, Al Sweidi S, Morin N, Estrada-Camarena E, Mendez P, Garcia-Segura LM, Di Paolo T. (2008) Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain. Journal of Steroid Biochemistry and Molecular Biology 108:327-338.

Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. (2007) Serum retinol binding protein-4, leptin and adiponectin concentrations are related to ectopic fat accumulation. J Clin Endocrinol Metab 92: 4883-4888.

Pozzi S., Benedusi V., Maggi A. And Vegeto E.. (2006) Estrogen action in neuroprotection and brain inflammation, Ann N.Y.Acad.Sci. 1-22 10.1196/annals.1386.035

Sanz A, Carrero P, Pernia O, Garcia-Segura LM. (2008) Pubertal maturation modifies the regulation of insulin-like growth factor-I receptor signaling by estradiol in the rat prefrontal cortex. Developmental Neurobiology, 68:1018-1028.

Stell A, Belcredito S, Ciana P, Maggi A. (2008) Molecular imaging provides novel insights on estrogen receptor activity in mouse brain. Molecular Imaging 7:283-292.

Tapia-Gonzalez S, Carrero P, Pernia O, Garcia-Segura LM, Diz-Chaves Y. (2008) Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs. Journal of Endocrinology, 198:219-230.

Vegeto E, Benedusi V, Maggi A. (2008) Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases. Frontiers in Neuroendocrinology 29:507-519.

Veiga S, Carrero P, Pernia O, Azcoitia I, Garcia-Segura LM. (2007) Translocator protein (18KDa) is involved in the regulation of reactive gliosis. Glia 55:1426-1436.

Yague JG, Wang AC, Janssen WG, Hof PR, Garcia-Segura LM, Azcoitia I, Morrison JH. (2008) Aromatase distribution in the monkey temporal neocortex and hippocampus. Brain Research 1209:115-127.

Books and book chapters

Hardman MJ and Ashcroft GS (2007) MIF: wound repair. In MIF: a most interesting factor, World Scientific Publishing.

Hardman MJ and Ashcroft GS. (2006) The foot in Diabetes, 4, WILEY