Press Release

Menopausa, ci aiuteranno i topi a salvare gli estrogeni (Menopause, mice will help us to save estrogens) Magazine Corriere della Sera 17 Maggio, 2007
Adriana Maggi, coordinator of the European research group EWA, describes the role played in the project by transgenic animals. It is foreseen that, thanks to engineered mice, in a few years biological markers of estrogen action will be made availble to study novel and better focussed therapies.

Invecchiamento della donna - Luci ed ombre nella cura della menopausa (Woman aging - Light and shade in menopause therapy) Quaderni della SIF Ottobre 2006
As reported by the coordinator Adriana Maggi, EWA group reviews on the state of the art of the therapy for postmenopausal women.

Dalla TOS di soli estrogeni nessun danno mammario (No breast damage comes from estrogen-only replacement therapy) Corriere Medico May 4, 2006
Adriana Maggi, EWA Coordinator, comments on recent reanalysis of Women's Health Initiative study showing that long term treatment with estrogen alone reduces cumulative risk of breast cancer.

Menopausa: con EWA si ricomincia da capo (Menopause: re-starting from the beginning with EWA) – Occhio Clinico – April 30, 2006
EU project EWA is the first European project aimed at understanding the physiological bases of women’s ageing. Little is known so far about estrogen effects on the central nervous system, the cardiovascular system or the skeletal system: this is why basic science from eight among the most advanced European research groups in the field will still help developing novel and safer replacement therapy.

Nelle donne più giovani l'estrogenoterapia vale (Estrogen therapy works in younger women) Corriere Medico April 20, 2006
EWA Coordinator, Prof. Adriana Maggi, refers on EWA point of view on currently used ERT and on the need of novel and more personalized therapies, after the publication of the latter analysis of Women's Health Initiative study on ERT and cardiovascular risk in younger postmenopausal women.

Menopausa: con EWA si ricomincia da capo (Menopause: re-starting from the beginning with EWA) – www.spaziodonna.com – April 18, 2006
EU project EWA is the first European project aimed at understanding the physiological bases of women’s ageing. Little is known so far about estrogen effects on the central nervous system, the cardiovascular system or the skeletal system: basic science from eight among the most advanced European research groups in the field will help developing novel and safer replacement therapy.

EWA Estrogen & Women Aging – DocMagazine – March/April, 2006
An Italian coordinator, Adriana Maggi, will lead the European project EWA, which will investigate on the physiological role of estrogen on non-reproductive cells in order to develop novel and safer replacement therapies, which will become more and more specific in timing and dosages to each woman’s needs.

Terapia ormonale sostitutiva e menopausa: con il progetto EWA si ricomincia da capo (Hormone replacement therapy and menopause: a new start with the project EWA) – Congress Digest – March 31, 2006
A new European research programme, involving eight among the most advanced group in the field of estrogens, will investigate on the effects of female hormones on non-reproductive organs, to find out novel and safer replacement therapies, free from adverse side-effects.

Al via un nuovo progetto per conoscere meglio gli estrogeni (A novel project to deepen knowledge on estrogen is ready to go) – La Neurologia Italiana – March 31, 2006
The Center of Excellence for Neurodegenerative Diseases of the Unversity of Milan will coordinate a European Research project, EWA, which will work to understand the physiological bases of women’s ageing. This will help in developing novel replacement therapies, active through estrogen receptors.

Estrogeni sotto i riflettori (Estrogens in the spotlight) – Medici Oggi – March 31, 2006
The European project EWA, coordinated by the, focuses on the effects of estrogen on non-reproductive tissues, to develop novel instruments to generate novel and safer replacement therapies.

Donne e menopausa, un futuro senza segreti (Women and menopause, no secrets for the future) – Punto Effe – March 23, 2006
After understanding that knowledge on the physiological roles of estrogen is nowadays still too scarce, EWA will pursue the development of novel models in which to study them to come to the development of novel systems for the validation of safer replacement therapies.

EWA: un progetto europeo sui recettori degli estrogeni (EWA: a European project on estrogen receptors) – MD – March 01, 2006
The European project EWA will try and design novel models to test current and innovative replacement therapies in order to dissect their beneficial effect on target organs from undesired side-effect, by investigating the molecular mechanisms underlying estrogen receptor action.

Menopausa, si ricomincia da capo – Un progetto della Comunità Europea (Menopause, starting again from the beginning – A European Union Project) – Quaderni della SIF, Vol. 5 – March, 2006
After the confusion brought about in the field by the results of the WHI study, EWA will investigate both on the role of estrogens on non-reproductive tissues during premenopausal years and on the effects of estrogen loss during menopause. This new knowledge will lead to the development of safer therapies, thanks to the cooperation of eight groups, among the more advanced in estrogen research.

Il primo progetto europeo coordinato da un Centro italiano studia l’effetto degli estrogeni sugli organi in post-menopausa (The first European project, coordinated by an Italian Center, studying the effects of estrogens on the organs during post-menopause) – Doctor – February 28, 2006
Still little is known about estrogen role on non-reproductive tissues such as central nervous system, skeletal system and cardiovascular system. EWA project will clarify these points with the aid of basic science in order to develop validated models necessary to provide novel therapies.

Estrogeni, task force per conoscerli meglio (Estrogens: a task force to know them better) – Giornale del Medico – February 27, 2006
In order to increase knowledge about the role of estrogens on non-reproductive organs, the European project EWA will generate cellular and animal models in which to investigate estrogen effects, to finally exploit the results in the screening of novel drugs to be potentially introduced for replacement therapies.

Estrogeni: l’indagine di EWA (Estrogens: EWA’s research) – Il Farmacista – February 23, 2006
The European project EWA, with the participation of the main European research groups on estrogens, aims at understanding modalities, doses and timing of replacement therapy administration to reduce the insurgence of undesired effects.

Estrogeni: un nuovo progetto europeo (Estrogens: a novel European project) – Tempo Medico – February 23, 2006
After understanding that current replacement therapies have severe undesired effects, EWA will investigate on the role of estrogens on non-reproductive tissues to develop safer therapies active on selective target organs, through the collaborative efforts of eight groups, among the more advanced in estrogen research.

Jane Seymour: “Così ho vinto la menopausa” (Jane Seymour: “The way I won over menopause”) – Grazia – February 21, 2006
Adriana Maggi, who coordinates the European project EWA, underlines that women have to reach personalized therapies to cope with menopausal symptoms, and EWA is investigating to increase the poor knowledge available at present about the way each woman’s body reacts to replacement drugs.

EWA per la salute della donna (EWA for women’s health) – Il Sole 24 Ore Sanità – February 20, 2006
The main purpose of EWA is to understand the bases of women’s aging to design novel safer therapies, after the current ones have proven to lead to undesired side-effects. The Center of Excellence on Neurodegenerative Diseases (CEND) of the University of Milan will coordinate a panel of experts in the field of estrogen research.

Menopausa: con EWA si ricomincia da capo (Menopause: re-starting from the beginning with EWA) – www.doctor33.it – February 15, 2006
The European project EWA, coordinated by the Center of Excellence on Neurodegenerative Diseases (CEND) of the University of Milan, focuses on the effects of estrogen on non-reproductive tissues, to develop novel instruments to generate novel and safer replacement therapies.

Estrogeni in corpo (Estrogens within) – Io Donna – February 11, 2006
After understanding that current replacement therapies have severe undesired effects, EWA will investigate on the role of estrogens on non-reproductive tissues to develop safer therapies active on selective target organs.

Salute: EWA, per capire meglio la menopausa (Health: EWA, for a better understanding of menopause) – www.intrage.it – February 06, 2006
The European project EWA will try and answer a series of open questions on menopause, to design safer protocols for replacement therapy: what is the effect of the loss of estrogen on non-reproductive tissues? Do we need novel drugs or shall we change the administration route and timing of old ones?

Ormoni in menopausa, si ricomincia (Hormones during menopause, a new start) – Io Donna – February 4, 2006
After the results of the U.S. WHI clinical study, which have cast only doubts in the field of hormones and menopause, a new European study will go back to basic science to unravel the mechanisms of estrogen action, to develop novel and safer therapies.

Quali estrogeni in menopausa e quando? (What kind of estrogen should we use in menopause and when?) – Corriere della Sera.it/Salute – February 03, 2006
The European project EWA will try and design novel models to test current and innovative replacement therapies in order to allow women choose the therapy that is most suitable for her symptoms and needs, after the observation that women respond differently from one another to the same therapy.

EWA: il primo progetto europeo per capire le basi fisiologiche dell’invecchiamento della donna (EWA: the first European project to underatand the physiological bases of women’s aging) – www.saluteeuropa.it – February 02, 2006
Still little is known about estrogen role on non-reproductive tissues such as central nervous system, skeletal system and cardiovascular system. This is what EWA project will clarify to develop novel and safer replacement therapies for the menopause.

Ormoni femminili: parte il progetto EWA per saperne di più (Female homones: the newborn project EWA to learn something more about them) – Yahoo! Salute – February 02, 2006
Still little is known about estrogen role on non-reproductive tissues such as central nervous system, skeletal system and cardiovascular system. EWA project will clarify these points to develop novel and safer replacement therapies for the menopause and to design novel administration modalities.

Menopausa: con EWA si ricomincia da capo (Menopause: re-starting from the beginning with EWA) – www.paginemediche.it – January 30, 2006
The European project EWA, coordinated by the Center of Excellence on Neurodegenerative Diseases (CEND) of the University of Milan, focuses on the effects of estrogen on non-reproductive tissues, to develop novel instruments to generate novel and safer replacement therapies.

Scienziata milanese guida colleghi di 8 centri europei, primi risultati tra tre anni (A researcher from Milan guides colleagues from 8 European centers, the first results expected for in three years) – Notiziario Adnkronos Salute – January 30, 2006
Adriana Maggi directs the Center of Excellence on Neurodegenerative Diseases (CEND) of the University of Milan and coordinates EWA, an EU funded research project to unravel the mechanisms of woman’s aging to develop novel and safer therapies.

Primo studio europeo per la terapia sostitutiva della menopausa (First European study for menopause replacement therapy) – ANSA Salute – January 30, 2006
EWA, the first European study on menopause replacement therapy, will be coordinated by the Center of Excellence for Neurodegenerative Diseases of the University of Milan and will develop novel models in which to test the safety of novel therapies, will investigate on the physiological response of the body to estrogen, and will give novel bases on which to choose and optimize the therapy for each woman.